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Semaglutide requires a gradual titration schedule, typically starting at 0.25 mg and increasing every four weeks

Research consistently shows that weight regain commonly occurs after discontinuation of GLP-1 therapy

For those exploring the full landscape of what peptides and GLP-1 compounds can do for body composition, the peptides for fat loss resource and the peptides for muscle growth guide provide broader context on how different compounds interact with body recomposition goals

Engaging in regular physical activity, including weight-bearing exercises a couple times a week, while on semaglutide is important for maintaining muscle mass and potentially enhancing the medications effects