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Other risk factors that may increase vulnerability include: Long duration of diabetes (typically more than 10 years) Poor glycaemic control prior to starting GLP-1 therapy (HbA1c significantly above target) Rapid reduction in HbA1c (a drop of more than 2 percentage points [22 mmol/mol] within 36 months) Concurrent hypertension , especially if poorly controlled Diabetic kidney disease (nephropathy), which often correlates with retinopathy severity Previous history of retinal treatment (laser photocoagulation or intravitreal injections) People with type 2 diabetes but no retinopathy appear to have minimal risk of retinopathy progression based on current evidence
The specific reason for use affects dose targets, titration, and monitoring
The underlying concept - that gut microbiome composition and function can influence metabolism - is supported by published research
Por otro lado, tambin reducen la secrecin de glucagn, una hormona que incrementa los niveles de glucosa en sangre, contribuyendo as a un mejor control glucmico
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