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It is involved in a variety of physiological processes, including cell proliferation, apoptosis, migration and immunity

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10.1016/j.jece.2015.03.027 48 MinaiyanM.AsghariG.TaheriD.SaeidiM.Nasr-EsfahaniS

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85 The conflicting triangle framework highlights a context-dependent interplay in which tumor cell-intrinsic immune checkpoint signaling remodels the TME via EMT induction and autophagy-mediated immune regulation, contributing to immune evasion and resistance

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PLoS One 2021;16:e0253543

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