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Unresolved safety questions The staff review identified uncertainty about immunogenicity, aggregation, peptide-related impurities, hypersensitivity, route-specific risk, repeated exposure, and long-term use
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[15] [16] Tests may include full blood count, serum B12 levels, anti-intrinsic factor antibodies (to diagnose pernicious anaemia), and sometimes methylmalonic acid or homocysteine levels when the diagnosis is uncertain
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