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2010 December;11(6): 508513

10.1038/nature12721 33 GaoY.NananR.MaciaL.TanJ.SominskyL.QuinnT

There is little scientific evidence to support such health and wellness claims in humans

Moreover, the data used for this model did not extend beyond 52 weeks, necessitating extrapolation

A 2022 cross-sectional survey of 1,248 women taking spironolactone for dermatological indications, published in the Journal of the American Academy of Dermatology , found that 31% reported improved mood and 19% reported improved sleep quality after 3 months on therapy