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Chronic TLR5 signaling in ovarian cancer impairs CD8 T cell activation by disrupting XCR1CD103 cDC1 differentiation and expanding immunosuppressive programmed death ligand-1 (PD-L1) myeloid subsets [351]

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[1] References: MHRA/EMC Summary of Product Characteristics: Mounjaro (tirzepatide) NICE Technology Appraisal: Tirzepatide for managing overweight and obesity NICE NG28: Type 2 diabetes in adults: management Understanding the side effect profile of Mounjaro is essential for patients and healthcare professionals, particularly when distinguishing it from steroid medications, which have an entirely different adverse effect spectrum