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The result has been an explosion in demand, with roughly 40 million Americans having tried a GLP-1 for weight loss, according to a 2026 RAND report
Blache D, Gesquire L, Loreau N, and Durand P (1999)
References Nakamura A, Nakashima M, Sakai K, Niwa M, Nozaki M, Shiomi H
This improvement appears to be linked to GLP-1 s ability to reduce the pro-inflammatory cytokines responsible for the persistence of the disease
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