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The influence of polysaccharides from Ophiopogon japonicus on 2,3,5,4-tetrahydroxy-stilbene-2-O--d-glucoside about biopharmaceutical properties in vitro and pharmacokinetics in vivo
Compared to the reference SGLT1/2DPP-4 scaffold, i optimized strongly this molecule and my new structure displays a markedly improved balance between target engagement and systemic exposure
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