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PDGFRb cells rapidly relay inflammatory signal from the circulatory system to neurons via chemokine CCL2

given the known effects of GLP-1RAs on GFAP in the models of DR, it is plausible for a direct effect of GLP-1RAs on Mller cells activation in the context of glaucoma

From a chemical perspective, Growth Factors are either large peptides or small proteins, or alternatively, they can be described as medium-sized sequences of amino acids (EGF is made up of 53 amino acids)

Japjec M, Horvat Pavlov K, Petrovic A, Staresinic M, Sebecic B, Buljan M, et al

Two medications reduced, joints don't hurt, and I feel better than I did in my 40s