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Scientific Basis and References
To evaluate whether this increase in insulin secretion could be attributed to an increase in cell mass and/or an enhanced secretory capacity of the islets, immunohistochemical analysis of the pancreas and glucose-stimulated insulin secretion (GSIS) assay were performed
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Tirzepatides additional GIP receptor activity makes it distinct from Trulicity and may contribute to its enhanced effects on weight loss and metabolic health
These SCFAs activate free fatty acid receptors (FFAR2 and FFAR3) on intestinal L-cells, directly stimulating GLP-1 secretion
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