PMID: 41901308
Notably, the combination of AOD9604 and HA appeared to offer greater benefits than either agent alone, suggesting a synergistic effect in promoting cartilage protection and repair [1]
Vitamin B12 deficiency If left untreated, vitamin B deficiency can harm your brain and nervous system, leading to issues such as: Incontinence (not being able to control your pee or poop) Nerve issues, such as numbness, weakness, or nerve pain Erectile dysfunction (not being able to get an erect penis) Paralysis (not being able to move your body) Memory loss Paranoia (feeling like others are trying to hurt you) If you dont have symptoms but are at risk of low B12 levels, your doctor might also want you to have regular tests
If a vegetarian mother has low or borderline B12, her exclusively breastfed infant may become deficient within the first few months of life, with consequences for the babys developing nervous system
Researchers examining potential neurological or cognitive effects often prefer the nasal route because it provides more direct access to the central nervous system