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The most important unresolved safety-related research gaps include long-duration exposure, broader dose-response toxicology, sex-specific effects, reproductive and developmental endpoints, hematology, immune monitoring, genotoxicity assessment, and comprehensive off-target profiling across methyltransferase and non-methyltransferase targets

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Glutathione reductase

This is principally true in the case of New Yorks existing 1115 waiver

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