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This difference in mechanism is precisely why researchers became so interested in combining cagrilintide with GLP-1 therapy
Earlier animal studies with malnourished mothers reported that delayed ossification is associated with decreased maternal body weight, and maternal malnutrition or reduced intake are common pathways to decreased fetal weight/growth and ossification (6669), but malnutrition models did not report the increase in major congenital anomalies reported after gestational exposure to GLP-1 agonists
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