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Protein concentrations were again determined spectrophotometrically at 280 nm

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Multiple immune pathways, such as TLR, IL-1R, tumor necrosis factor receptor (TNFR), growth factor receptor (GF-R), and protein kinase C (PKC), can converge on NF-B to potently enhance STING-mediated immunity by inducing microtubule depolymerization, which blocks STING lysosomal degradation and prolongs its activation

Thus, our studies have unfolded a role of the PRR-25HC-integrin-FAK-NFB signaling network in amplifying inflammatory response

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