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1,5 Healthy fats Monounsaturated and polyunsaturated fatty acids (MUFAs and PUFAs, respectively) enhance GLP-1 secretion through free fatty acid receptor and G-protein-coupled receptor signaling pathways, including GPR40, GPR119, and FFAR1/3

423 Furthermore, the study emphasized that neurons in specific brain regions, such as the hindbrain and hypothalamus, co-express GLP-1R along with 1-adrenergic and -opioid receptors, suggesting a localized mechanism within the CNS that could coordinate peripheral anti-inflammatory responses