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The accumulation of SFAs contributes to gut microbial dysbiosis, promoting the proliferation of sulfate-reducing bacteria such as Bilophila wadsworthia and inflammatory bacteria like Enterococcus faecalis , while suppressing beneficial microbes

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Furthermore, precision medicine shows promise in this field, but more study is needed to discover reliable biomarkers or clinical traits that can predict individual reactions and aid in patient selection

101-6, PMID 2205455

If those dont work, they might then approve a newer drug like Wegovy