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(1992) A multicenter study of the effects of vitamin B12 on sleep-waking rhythm disorders: in Shizuoka Prefecture
For example, one study found that after taking 1,000 mcg of oral vitamin B12, only about 1.3% (13 mcg) is absorbed into the bloodstream
The higher doses and costs are justified by accelerated timelines in appropriate contexts
Localized injections may still have a role in some situations, but healing is usually influenced by much more than simply placing a needle into the exact area of pain
Decrease dose if: Experiencing consistent side effects (headaches, fatigue, GI disturbance), achieving satisfactory results at current dose with no need for escalation, or cost considerations favor using minimum effective dose
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