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If the blood-testis barrier becomes compromised through events (eg, surgery or infection) or due to vascular abnormalities (eg, varicocele), the development of antisperm antibodies, which target sperm and decrease their motility, can occur

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In brief, the N-terminal and transmembrane region of one receptor and the C-terminal tail of the other receptor were amplified with primers that introduced a HindIII restriction site directly upstream of the start codon of the receptor and replaced the stop codon with an XbaI restriction site (primers are shown in Supplementary Table 1)

TB-500 is a synthetic fragment of TB4 that is also found on the peptide market