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This synergy is driven by ER stress and a pro-apoptotic unfolded protein response, indicating the potential for adjuvant therapies in CRC
Methods This real-world retrospective cohort study used Truveta Data, which includes de-identified electronic health record (EHR) data from more than 120 million patients across the US
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While animal studies cannot definitively rule out human cancer concerns, the consistent absence of tumors or pre-cancerous changes across multiple species, dosing regimens, and administration routes carries meaningful weight
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