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Metformin and Ozempic can be prescribed together as part of a combination therapy to manage diabetes

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Central nervous system effects include appetite suppression through actions on hypothalamic centers that regulate hunger and satiety

Key points Leg cramps (especially calves and feet) are most commonly reported Nighttime cramps and post-exercise cramps appear most frequently Duration typically ranges from seconds to minutes per episode Intensity varies from mild discomfort to painful spasms that wake patients from sleep Managing muscle cramps Most Mounjaro-related muscle cramps can be effectively managed with simple strategies