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These include nausea, vomiting, and diarrhea, which are common to all incretin mimetics
When used as monotherapy or with medications that do not independently cause hypoglycemia, tirzepatide has a low intrinsic risk of causing clinically significant hypoglycemia
doi: 10.1098/rstb.2012.0212 132 McCleanP
More serious but less common adverse effects that warrant prompt medical attention include: Acute pancreatitis: Seek urgent medical review if you experience severe, persistent abdominal pain, particularly if it radiates to the back Gallbladder disease: Rapid weight loss associated with GLP-1 class agents may increase the risk of gallstones
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