glp-1 nejm In an earlier analysis of the SURMOUNT-1 trial, tirzepatide (a dual glucose-dependent insulinotropic polypeptide [GIP] and glucagon-like peptide -1 [GLP-1] receptor agonist) was shown to provide substantial and sustained reductions in body weight The expanding landscape of GLP-1
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![glp-1 nejm In an earlier analysis of the SURMOUNT-1 trial, tirzepatide (a dual glucose-dependent insulinotropic polypeptide [GIP] and glucagon-like peptide -1 [GLP-1] receptor agonist) was shown to provide substantial and sustained reductions in body weight The expanding landscape of GLP-1](https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41591-025-04124-5/MediaObjects/41591_2025_4124_Fig2_HTML.png)
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