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a high-cardiovascular-risk kidney cohort showed a slower decline in kidney function and about a third less protein leak, which travels to a similar-risk body, not a healthy one. Lean and metabolically healthy: a safety read, not an efficacy target No long trial has tested tirzepatide in lean, metabolically healthy people
PMID 35337622
AKB-6548, a new hypoxia-inducible factor prolyl hydroxylase inhibitor increases hemoglobin while decreasing ferritin in a 28-day, phase 2a dose escalation study in stage 3 and 4 chronic kidney disease patients with anemia [abstract]
These conditions involve impaired copper handling that could make even topical copper application problematic
While side effects are rare, patients may experience mild swelling and redness, which typically subside within 2 to 3 days
