Blanco-Anesto, A
Similarly, two subtypes of early-onset Parkinsons disease (PD), XPDS and Kufor-Rakeb syndrome, are both related to disorders of lysosomal acidification 127,128 , indicating that lysosomal deacidification accelerates the development of PD-like neuropathology
Similar results have been shown in HSV-1-infected rat cortical neurons (De Chiara et al., 142 , and that a synthetic peptide of gB is able to self-assemble into -sheets with similar conformation to A and produce accumulation of neurotoxic A fibrils (Cribbs et al., 2015)
the effect remains weak and not significant for doses 2, 4 and 8 times higher respectively
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