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In pregnant women, vitamin B12 helps develop the fetus properly, specifically when it comes to nerve and eye development

As fat tissue grows and more NNMT is produced, higher amounts of hormones and pro-inflammatory signals are produced that are responsible for weight gain and other chronic diseases such as type 2 diabetes and cardiovascular disease. NNMT is responsible for converting nicotinamide (NA) into 1-methylnicotinamide (1-MNA), which takes it out of the NAD salvage pathway (see the diagram below)

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doi:10.1002/14651858.CD004514.pub2

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