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Ann Neurol 35:181188
In a larger 36-week trial with children, caregiver ratings indicated substantial improvements in irritability, but measures of overall autism severity, like the Ohio Autism Clinical Impressions Scale (OACIS), showed only small, non-significant gains
In fibrosarcoma and osteosarcoma models, ketotifen combined with pegylated liposomal doxorubicin (PLD) or pegylated liposomal coencapsulated alendronate-doxorubicin (PLAD) plus anti-PD-1 antibody improved antitumor responses, increased cytotoxic CD8+ T cell and CD4+ T helper cell infiltration, and Treg numbers
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