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The consistency of GLP-1 effectiveness across alcohol, opioids, cocaine, nicotine and cannabis suggests these drugs may act on a shared vulnerability underlying addiction not on any single substance pathway
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If you are concerned about how your medication is affecting your relationship with food, the right step is to raise this with your doctor and to seek a specialist eating disorder assessment
When amino acids reach the small intestine, they directly trigger L cells to release GLP-1 through nutrient-sensing mechanisms involving the calcium-sensing receptor (CaSR) and peptide transporter 1 (PEPT1)
Conclusion This study provides preliminary evidence in support of GLP-1 based therapies in providing beneficial effects against atherosclerosis as this therapeutic regimen was found to be associated with statistically significant reductions in the plasma levels of atherosclerosis markers including plasminogen activator inhibitor-1, high sensitivity c-reactive protein and brain natriuretic peptide
