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Mendelian randomization (MR) was used to evaluate the causal relationships between exposure and outcomes

Clin Endocrinol (Oxf) 1974;3:48993.PubMed 23

That assumption can backfire

Preclinical models indicate that the GLP-1 R system has evolved, at least in part, to regulate feeding-related motivation ( Repeated dosing is probably crucial for positive effects in depression and suicidality