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Vesicles progress to ulcerated/aphthous lesions and may coalesce.17 A possible complication of HZ infection of the trigeminal or maxillary facial nerve is the development of cranial and peripheral paralysis, such as Ramsay-Hunt syndrome, in which the patient develops Bell's palsy, vesicles in the external auditory canal, and loss of sensation in both anterior thirds of the tongue.18 Focal epithelial hyperplasia Focal epithelial hyperplasia, also called Heck's disease, has been described in Native American and Inuit populations

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Others are more conservative due to concerns about the high costs, access issues, side effects, and lack of longitudinal data on long-term outcomes

[1] [2] The weight reduction and improved insulin sensitivity contribute to favorable changes across multiple cardiometabolic risk factors

According to CDC data, non-Hispanic Black and Hispanic adults have the highest prevalence of obesity in the U.S