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Consistent with this use of a reporter mouse together with a number of validation approaches the GLP-1R was identified in chief cells, parietal cells and Brunners glands ( 125 I-labeled GLP-1 also demonstrated a strong signal in stomach parietal cells, basolateral epithelial cells in the duodenum, Brunners glands and the myenteric nerve plexus (Pyke et al., 2014)
Metabolites are the products of enzyme-catalyzed reactions that occur naturally within cells
Wood says, because GLP-1s suppress appetite and slow gastric emptying, patients may unintentionally drink less throughout the day
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