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Diabetes Care 42(6):11471154
AST, ALT, GGT, and bilirubin
Semaglutide in Adults with Overweight or Obesity (NEJM) Systematic Review: GLP-1 & Peptide Approaches to Obesity broad meta-analysis of peptide drug clinical trials including semaglutide, liraglutide, and tirzepatide showing significant weight reduction benefits
Animal studies use controlled purity, defined dosing, and monitoring that home use cannot replicate, and they still do not answer questions about long-term human exposure, immunogenicity, or rare serious events
Zrelli H, Kusunoki M, Miyazaki H
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