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The SELECT trial, which included patients with CV disease and overweight or obesity (many also had increased risk for diabetes), showed a reduction in major adverse CV events (defined as CV death, nonfatal heart attack, and nonfatal stroke) of 20% with weekly subcutaneous semaglutide 2.4 mg

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There is a direct correlation with the speed of aging and the reduction of glutathione concentrations in intracellular fluids

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After a first 10-day period of intramuscular injections ALC 500 mg b.i.d., patients received an oral treatment consisting of one tablet of ALC 500 mg b.i.d., for 110 days