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Wegovy, also given once weekly, was first approved in 2021 for weight loss in adults with obesity

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Candidates typically include individuals with a BMI of 30 or higher, or those with a BMI of 27 or higher who have associated health risks like hypertension, dyslipidemia, or sleep apnea

Even researchers targeting 12mg will spend their first four weeks at 1mg, making this the dose level every single protocol participant experiences

The SwissKASH system we developed relies on tagging zDHHCs at their C-terminus with the KASH domain of syne-1/nesprin-1 for the ectopic ONM targeting