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It has been shown that mitochondria-free axon terminals of hippocampal or cortical neurons accumulate more Ca 2+ in response to repetitive stimulation, which promotes increasingly more SV release [55, 56]

Clinical Efficacy of Sodium-Glucose Cotransporter 2 Inhibitor and Glucagon-Like Peptide-1 Receptor Agonist Combination Therapy in Type 2 Diabetes Mellitus: Real-World Study

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