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Not dosage or injection frequency
63,64 In addition, loss of Tbc1d4 in mice that phosphorylated by Akt leads to the attenuation of downstream target activation of Rab-GTPase proteins associated with GLUT4 vesicles, and completely abolishes insulin-stimulated adipocyte glucose uptake
These findings are still emerging, and much of the research to date comes from animal and laboratory studies
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Older adults, vegans, individuals with gastrointestinal conditions, and those taking metformin or proton pump inhibitors often require higher doses or supplementation
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