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These observations suggest that mild inflammatory stimuli can activate endogenous defense mechanisms that strengthen the BBB and the overall CNS resilience

The SURMOUNT trials in patients without diabetes showed even greater weight loss, with the 15 mg dose producing an average loss of 20.9 percent of body weight at 72 weeks compared to 14.9 percent for semaglutide in similar populations

- MARGOLINA, A

Guidance for industry: Immunogenicity assessment for therapeutic protein products