Store sealed, lyophilized peptides protected from light and humidity at -4F or colder
however, some clinicians prefer to apply only bland, well-tolerated products (such as sterile hyaluronic acid) immediately post-needle and reserve active peptides for once the acute barrier disruption has calmed, precisely to limit irritation and copper exposure through wide-open channels
The most commonly reported side effects in clinical trials are nausea, vomiting, diarrhoea, and constipation consistent with the gastrointestinal effects seen with GLP-1 monotherapy
However, N-terminal modifications, such as N-acetylation, D-norleucine substitution, or replacement with -aminobutyric acid (GABA), dramatically elongated the peptides half-lives
In some embodiments, the formulation contains 3-7 mg/ml semaglutide