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The primary monotherapy dose-ranging evidence is a single trial: Lau and colleagues, published in The Lancet in 2021 (ClinicalTrials.gov NCT03856047 ) [5]
Up-to-now, these pathways are considerably less explored than the main SELENOP/LRP8 pathway, probably, owing to their supplementary function, which may take over only under specific conditions such as SELENOP or LRP8 deficiency
Aliquoting prevents repeated freeze-thaw cycles
Light walking after meals can actually help with digestion and reduce reflux risk
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