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A pharmacophore model from the 5UOY16j complex was used to screen the ZINC database, yielding 11,126 hits, which were narrowed down to 4 candidates, namely, compounds 23 , 24 , 25 , and 26 (ZINC00552773, ZINC75914738, ZINC73091800, and ZINC15933417) using Lipinskis rule, the PFS filter, and the SwissADME server (Figure 8)
ARA-290 (cibinetide) is an 11-amino-acid peptide derived from the tissue-protective region of erythropoietin
This is partially due to low success rates of smoking cessation during pregnancy (Glover et al., 2006
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