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8,9 Table 1 Risk Factors for Vitamin B12 Deficiency A multicenter randomized controlled trial of 390 patients with diabetes mellitus showed that those taking 850 mg of metformin three times per day had an increased risk of vitamin B 12 deficiency (number needed to harm = 14 per 4.3 years) and low vitamin B 12 levels (number needed to harm = 9 per 4.3 years) vs
Theres no quality control standard for products labeled for research use only which is why sourcing from a reputable veterinary compounding pharmacy matters a lot
Always follow medical guidelines and consult with a healthcare professional for personalized recommendations
There is no research showing that taking well over the recommended daily or weekly amount of B12 can be unsafe or detrimental to your health, and an official upper tolerable intake level has yet to be established
It is given once in a week for 6 weeks
