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The enzymes affected belong to one of three categories: Very long-chain acyl-CoA dehydrogenase (VLCAD): The symptoms that result from deficiencies in VLCAD were originally ascribed to loss of long-chain acyl-CoA dehydrogenase (LCAD) activity

The FDA is also reviewing nerandomilast for the treatment of PPF with a decision anticipated in early January 2026

References Rivas S, Pandya AG

Sweetwyne et al., 2017

Building on the success of the JDC1 and inspired by the technology of the groundbreaking JDC2 IP, the JDC Burst 1 was designed as a powerful successor to the JDC1 , setting new standards in brightness, color variety, and flexibility