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Description

Compound 4 demonstrated comparable potency to 3 (EC 50 = 4.6 M

Dopamine transporter density and behavioral response to methylphenidate in a hyperlocomotor rat model

Functional changes Phagocytosis Since monocytes and macrophages can enter the CNS in PD [28, 104], both cell types could be involved in the recognition of protein components and cellular debris [105, 106] and in the activation of phagocytotic mechanisms