Some people notice side effects for a longer period, particularly if their dose is increased too quickly or if their digestive system is more sensitive
GLP-1 is also known to delay the movement of food from the stomach to the small intestine after a meal
doi: 10.3389/fonc.2026.1834606 Received 19 March 2026 Revised 09 May 2026 Accepted 13 May 2026 Published 28 May 2026 Volume 16 - 2026 Edited by Fahui Liu, Xiamen University, China Reviewed by Armando Patrizio, Memorial Sloan Kettering Cancer Center, NY, United States Qiming Gong, Affiliated Hospital of Youjiang Medical University for Nationalities, China Hao Ling, Technical University of Munich, Germany Updates Copyright 2026 Kennedy, Thomas, DArcy, Odia, Kamdar, Pereira, Scarola, Miles, Frank, Taneja, Seetharamu and Mandal
I am indeed happy and satisfied with the results of your work
The starting dose of 0.25 mg once weekly for the first four weeks is primarily intended to improve gastrointestinal tolerability rather than provide maximum therapeutic benefit