This separation means synergistic benefits without receptor competition or diminished returns
However, the LC 50 value of MSNs-ss-SA was determined to be 1.98 mM, approximately six times greater than that of free SA ( LC 50 = 0.336 mM), indicating a significant reduction in toxicity due to the grafting of SA molecules onto MSNs-ss-NH 2
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In order to investigate the participation of GSH in cystine-induced cell signaling, we investigated the effects of cystine starvation on GSH homeostasis