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In addition, factors such as lipotoxicity, defects in the incretin system, hyperglucagonemia, increased renal glucose reabsorption, and central insulin resistance contribute to the progression of diabetes
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The disordered p53 transactivation domain is the target of FOXO4 and the senolytic [PMID: 40593617] Laboratory literature summary: The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4-DRI
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