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Acknowledgements The authors would like to sincerely thank the following individuals and institutions who made vital contributions to this study: We thank Rhyad Al-issa from the Department of Biochemistry, College of Medicine, King Khalid University, for his technical support in the preparation of the electron microscopic slides
Obesity treatments have been challenging, however, approval of Semaglutide or Wegovy, is a huge step in treatment of obesity
A separate phase 2a trial studied retatrutide specifically in metabolic dysfunction-associated steatotic liver disease (MASLD, the condition formerly framed as non-alcoholic fatty liver disease)
In phase II and III studies, people who took cagrilintide along with semaglutide lost up to 15.7% of their body weight, compared to 5.1% who took a placebo