More research is needed to fully understand this relationship.
When stratified by administration route, the mean percentage changes were: Intramuscular (IM): 307% Oral: 285% Sublingual: 199% IM administration showed the highest average B12 increase, although oral and sublingual routes also yielded substantial improvements, supporting their use as effective and less invasive alternatives
Third, most studies were designed to measure efficacy of healing, not to conduct rigorous, long-duration toxicology and carcinogenicity assessment following regulatory standards
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Some people might experience side effects