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Consequently, BBB dysfunction activates neuro-inflammatory pathways by increasing astro-glial activation, which in turn- increases BBB permeability and susceptibility of the CNS to foreign molecules (Yang et al., 2019)

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Chtioui H, Semela D, Ledermann M, Zimmermann A, Dufour JF (2007) Expression and activity of the cytochrome P450 2E1 in patients with nonalcoholic steatosis and steatohepatitis

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