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The mTOR pathway regulates cell growth and metabolism, and inhibiting it mimics the effects of caloric restriction, which has been linked to longevity
nature.com/articles/s4157 Insightful commentary in @Nature about rapid weight loss with GLP-1 meds which can lead to significant muscle loss or even #sarcopenia
20 DoveA.ShangY.XuW.GrandeG.LaukkaE.FratiglioniL.et al (2021)
However, ICIs can cause immune-related side effects (irAEs) by impairing peripheral immunological tolerance, and the endocrine glands are among the organs most frequently impacted
Inositol helps modulate the presence of insulin in the body, which may have significant effect on ovulation
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