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While the half-dozen men who spoke to me for this story largely said they had good experiences with compounded weight-loss drugs, doctors are concerned about the widespread use of compounded medications

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Gradual changes and consistent routines usually shorten the adjustment period

Limitations A key limitation of this review is the heterogeneity of HFpEF as a clinical syndrome, which includes a broad range of phenotypes and comorbidity profiles, limiting direct comparability across trials

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